Scientific Community: Testimonials

Bob Griffin chose Cambridge Isotope Laboratories, Inc. (CIL) for their proximity. But it’s their availability, competitive pricing, and high purity isotopes that’s kept me a customer. We rely on CIL for ¹³C glucose, ¹⁵N ammonium chloride, sometimes ¹⁷O water, and labelled amino acids. Their custom labelling, like sparse labelling, has been a game-changer for our NMR protein structure research. The stable isotope advantage? Non-perturbing labels, unlike fluorescent or EPR spin labels. My relationship with CIL? Very friendly, accommodating. They’ve become an essential partner in advancing our work. Considering CIL? Expect pure products, fair prices, timely delivery, and a willingness to handle special orders. I highly recommend them.

In this video, Professor Matthew Merritt from the University of Florida‘s Department of Biochemistry and Molecular Biology discusses his research in metabolic flux and imaging using dynamic nuclear polarisation (DNP). He shares his long-standing relationship with Cambridge Isotopes, citing their high-purity products as crucial for his work. Professor Merritt explains how Cambridge Isotopes’ custom-labelled substrates enhance his DNP experiments, which would be impossible with naturally abundant isotopes. He highlights the trust he has in the company due to their consistent responsiveness, high-quality products, and commitment to customer satisfaction.

Josh Coon, a chemistry professor at the University of Wisconsin in Madison, discusses his research group’s collaboration with Cambridge Isotope Laboratories (CIL). Five years ago, they approached CIL with an idea for a novel protein quantitation method requiring custom isotopically labeled lysine molecules. CIL collaborated with Coon’s team to develop these molecules, which enabled a quantitation method called “new code.” The partnership resulted in several publications and the method will soon become a commercial product. Coon praises CIL for their on-time delivery of pure isotopes, competitive pricing, and reliability, strongly recommending them to anyone using stable isotopes in their research.

Gary Patti, a professor at Washington University in St. Louis, discusses his research in metabolomics, which involves using mass spectrometry and NMR to study metabolism on a large scale. He has collaborated with Cambridge Isotope Labs (CIL) for about 6-7 years, finding their products consistently meet his needs at a reasonable price. Patti values the partnership with Cambridge Isotope Labs, emphasizing the scientific dialogue about creating new products beneficial to the field of metabolomics. He notes their active presence at metabolomics meetings and the friendships developed between his lab members and the Cambridge Isotopes team.

Jenny Van Eyk, director of the Advanced Clinical Biosystems Research Institute at Cedars-Sinai Medical Center, discusses her work on the challenging pipeline from discovery to patient care, with mass spectrometry and precise protein measurement at its core. Her lab uses isotopically labeled internal standards and peptides, supported by Cambridge Isotope Laboratories (CIL), to control variability across their research pipelines. Van Eyk emphasizes the transformative potential of high-quality reagents for reliable research and the importance of collaborating with organizations like CIL that share their commitment to quality, good science, and integrity.

David Muddiman, a professor at North Carolina State University, has partnered with Cambridge Isotope Laboratories (CIL) since the beginning of his independent career. David’s work in mass spectrometry relies on CIL’s high-quality, high-purity stable isotope-labeled compounds to make rigorous measurements and pursue scientific questions. David values CIL’s collaborative approach, proactive interest in understanding future needs, and willingness to suggest alternative products to enable better science. He appreciate CIL’s honesty, integrity, and commitment to continual improvement of their products. He feels that CIL provides more than just supplies, offering an infrastructure and collaborative mindset that enhances their research capabilities.

John Yates, a professor at The Scripps Research Institute, has spent 25 years involved in mass spectrometry research, with a current focus on animal disease models using stable isotope-labelled products from Cambridge Isotope Laboratories (CIL). His work encompasses a range of diseases including Alzheimer’s, cystic fibrosis, schizophrenia, and depression. The use of stable isotopes is essential for quantitative proteomics, with an initial focus on ¹⁵N (heavy nitrogen) for isotopic labelling of rats and mice. Yates emphasizes that the collaboration with CIL enables new experiments due to access to a wide variety of stable isotope-labelled materials. He describes the relationship with CIL as a partnership, highlighting their responsiveness, helpfulness, and commitment to timely delivery of high-quality products at affordable pricing.