Metabolism
Researchers employ stable isotope techniques to study a wide variety of metabolic disorders and diseases including Alzheimer’s, Parkinson’s, cancer, diabetes, and obesity. Isotopes are most commonly used in metabolism research as tracers to quantify biochemical or metabolic reactions in vivo. They can be used to study metabolic pathways, to determine biomarkers, to test the effects of a drug, and to develop metabolic profiles of biological systems in a particular state.
Product Grades
Cambridge Isotope Laboratories Inc. provides additional testing to many of our products as a service to our customers. The following documents describe the nature of these products, the different levels of control applied to them, and the Enhanced Technical Data Package that is available for some products.
Product Information and Resources
- Cancer Metabolism and Related Research
- Cellular Metabolism and Metabolomics
- Stable Isotopes in Drug Development and Personalized Medicine
- Product Quality Designation Chart
- 13C Enriched Substrates for Hyperpolarization
- Determining Protein Turnover in Fish D7 Leucine (Application Note 29)
- Analysis of Whole-Body Branched-Chain Amino Acid Metabolism in Mice Utilizing 20% Leucine 13C6 and 20% Valine 13C5 Mouse Feed (Application Note 43)
- Determination of Nitric Oxide Production and de novo Arginine Production with Stable Isotopes (Application Note 30)
- Tracing Lipid Disposition in vivo Using Stable Isotope-Labeled Fatty Acids and Mass Spectrometry (Application Note 31)
- Metabolic Incorporation of Stable Isotope Labels into Glycans (Application Note 23)
- Metabolic Isotopic Analysis Reveals Mitochondrial Loss of Function in pRb-Deficient Cells in vivo (Application Note 45)
- Enhanced Data Package
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