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Proteomics

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Metabolic Labeling

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Metabolic Isotopic Analysis Reveals Mitochondrial Loss of Function in pRb-Deficient Cells in vivo

Application Note 43

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Targeted LC-SRM/MS Quantification of Mammalian Synaptic Proteins with Mouse Express® Brain Tissue

Application Note 32

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Stable Isotope Labeling in Mammals with 15N Spirulina

Application Note 24

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Stable Isotope Labeling in Proteomics

Application Note 11

 

 

Chemical Tagging

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Individuality Normalization when Labeling with Isotopic Glycan Hydrazide Tags (INLIGHT™)

Application Note 37

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The Use of Adenosine 5'-Triphosphate for the Unambiguous Identification of Phosphopeptides

Application Note 17

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Specific Isotopic Labeling of Methyl Groups Has Extended the Molecular Weight Limits for NMR Studies of Protein Structure and Dynamics

Application Note 16

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Protein Expression

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 Full-Length Expressed Stable Isotope-Labeled Proteins for Quantification

Application Note 40

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Stable Isotope Dimethyl Labeling

Application Note 38

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 Heavy Labeled MS Protein Standards

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Stable Isotope-Labeled ApoA-1 as a Global Standard for Quantitative Proteomics Studies

Application Note 46

 

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Metabolic Research

 

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Metabolism

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Metabolic Isotopic Analysis Reveals Mitochondrial Loss of Function in pRb-Deficient Cells in vivo

Application Note 45

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Fluxing Through Cancer: Tracking the Fate of 13C-Labeled Energy Sources Glucose and Glutamine in Cancer Cells and Mouse Tumors

Application Note 34

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Tracing Lipid Disposition in vivo Using Stable Isotope-Labeled Fatty Acids and Mass Spectrometry

Application Note 31

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Determination of Nitric Oxide Production and de novo Arginine Production with Stable Isotopes

Application Note 30

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Determining Protein Turnover in Fish with D7-Leucine

Application Note 29 

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Metabolic Incorporation of Stable Isotope Labels into Glycans

Application Note 23

 

 

Metabolomics

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Thermo-CIL App Note Pathway Targeted Metabolomic Analysis in Oral-Head and Neck Cancer Cells Using IC-MS

Application Note 44

 

 

MS/MS Standards

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NSK-A-TS and NSK-B-TS Instructions for Use

Application Note 41

 

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Biomolecular NMR

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In situ Protein Expression

 

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Cell-Free Protein Synthesis with 2H/15N/13C-Labeled Amino Acids in H2O for the Production of Perdeuterated Proteins with 1H in the Exchangeable Positions

Application Note 36

 

 

In vivo Protein Expression

 

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Isotope Labeling of Alanine Methyl Groups on a Deuterated Background for NMR Studies of High-Molecular-Weight Proteins

Application Note 25

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[2,3-13C]-Labeled Aromatic Residues as a Means to Improving Signal Intensities and Kick-Starting the Assignment of Membrane Proteins by Solid-State MAS-NMR

Application Note 22

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Effective Site Specific Isotopic Labeling 15N, 13C Glycine; 15N, 13C Phenylalanine; 15N Tryptophan) Expression Optimization Using BioExpress® 2000 Media

Application Note 20

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In vitro Protein Synthesis of Perdeuterated Proteins for NMR Studies

Application Note 19

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Top Ten Tips for Producing 13C, 15N Protein in Abundance

Application Note 15 

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Efficient Uniform Isotope Labeling of Proteins Expressed in Baculovirus-Infected Insect Cells Using BioExpress® 2000

Application Note 14

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Optimization of BioExpress Supplementation of M9 Cultures

Application Note 12

 

Stereospecific Leucine/Valine Methyl Labelling

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Stereospecific Leucine / Valine Methyl Labelling

Application Note 48

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Membrane Proteins

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Uniform Isotope Labeling of Eukaryotic Proteins in Methylotrophic Yeast for High-Resolution NMR Studies – Extension to Membrane Proteins

Application Note 26

 

 

Selective Labeling

 

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Production of U-[2H], Thyr-γ2[13CH3] Labeled Proteins for Methyl-TROSY NMR

Application Note 39

 

 

Hyperpolarization/MRI/MRS

 

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Development of Hyperpolarized Metabolic Contrast Agents Using PASADENA

Application Note 21

 

 

Other BioMolecular NMR

 

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Using Stable Isotopes to Solve Problems in Combinatorial Chemistry

Application Note 1

 

 

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